KPTI · XBRL financial data
Karyopharm Therapeutics financial statements, every fiscal year
The same tables from 6 filings, lined up. Matched by XBRL tag: renamed lines keep their history.
How these numbers work
- Every number comes from the company's XBRL financial data filed with the SEC, and each one links to its filing.
- Lines are matched by XBRL tag, so a line renamed between filings keeps its history.
- * marks a quarter worked out from the filing totals: the 10-K year minus the first three quarters, or a year-to-date total minus the earlier one. Fourth-quarter earnings per share is fourth-quarter net income over the fourth-quarter weighted shares.
- 0 means a filing states zero; a dash (—) means no filing states that number.
- “year only” means the 10-K gives the full year but not the quarters needed to work out the fourth. A worked-out quarter of revenue, cost of revenue or operating cash flow more than twice the company's largest quarter of the two years before is shown this way too.
- Gross profit is shown as the company reports it; a worked-out quarter must equal revenue less cost of revenue for that quarter, or it is a dash.
- Operating income can be above gross profit when the company books other operating income between the two, shown on its own line.
- Shares outstanding come from each filing's cover page, as of the date printed there.
- Quarters are fiscal: Q2 FY27 is the second quarter of the company's fiscal 2027.
Income statement
CSVFiscal years (KPTI's year ends in late December)
| In millions of dollars | Dec 31, 2020 | Dec 31, 2021 | Dec 31, 2022 | Dec 31, 2023 | Dec 31, 2024 | †Dec 31, 2025 |
|---|---|---|---|---|---|---|
| Revenue from contracts with customers | 108 | 210 | 157 | 146 | 145 | 146 |
| Research and development | 151 | 161 | 149 | 139 | 143 | 126 |
| Selling, general and administrative | 126 | 144 | 145 | 132 | 115 | 105 |
| Total operating expenses | 280 | 308 | 299 | 276 | 265 | 237 |
| Operating income (loss) | (172) | (98) | (142) | (130) | (119) | (91) |
| Interest income | 3 | 1 | 2 | 11 | 7 | 3 |
| Interest expense | 27 | 26 | 25 | 24 | 37 | 46 |
| Other income (expense) | 0 | (0) | (0) | (0) | 28 | 0 |
| Income tax expense (benefit) | 0 | 0 | 0 | 0 | 0 | 0 |
| Net income (loss) | (196) | (124) | (165) | (143) | (76) | (196) |
| Earnings per share, basic USD per share | (2.72) | (1.65) | (2.02) | (1.25) | (0.63) | (17.93) |
| Earnings per share, diluted USD per share | (2.72) | (1.65) | (2.02) | (1.25) | (0.93) | (17.93) |
| Weighted average shares, basic millions of shares | 72 | 75 | 82 | 114 | 0 | 0 |
| Weighted average shares, diluted millions of shares | 72 | 75 | 82 | 114 | 0 | 0 |
- † Share count changed about 1/7 in the period ending 2025-12-31, likely a stock split with no split ratio in the XBRL data; figures before that column are not adjusted.
Balance sheet
CSVFiscal years (KPTI's year ends in late December)
| In millions of dollars | Dec 31, 2020 | Dec 31, 2021 | Dec 31, 2022 | Dec 31, 2023 | Dec 31, 2024 | †Dec 31, 2025 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 86 | 190 | 135 | 52 | 62 | 61 |
| Marketable securities | 163 | 38 | 143 | 139 | 46 | 3 |
| Marketable securities, non-current | 24 | — | — | — | — | — |
| Inventory | 3 | 4 | 4 | 3 | 5 | 4 |
| Prepaid and other current assets | 9 | 14 | 20 | 12 | 12 | 9 |
| Total current assets | 277 | 276 | 350 | 234 | 156 | 103 |
| Property and equipment, net | 2 | 2 | 1 | 1 | 0 | 0 |
| Right-of-use asset | 9 | 8 | 6 | 4 | 6 | 5 |
| Total assets | 313 | 305 | 358 | 240 | 164 | 108 |
| Accounts payable | 4 | 2 | 3 | 3 | 5 | 4 |
| Accrued liabilities | 53 | 69 | 58 | 61 | 61 | 64 |
| Total current liabilities | 60 | 74 | 66 | 69 | 92 | 92 |
| Lease liability, non-current | 11 | 9 | 6 | 3 | 7 | 6 |
| Total liabilities | 263 | 385 | 375 | 377 | 350 | 401 |
| Accumulated deficit | (1,070) | (1,179) | (1,344) | (1,487) | (1,563) | (1,759) |
| Total stockholders' equity | 51 | (80) | (17) | (136) | (186) | (293) |
| Total liabilities and equity | 313 | 305 | 358 | 240 | 164 | 108 |
| Common shares outstanding (cover page) millions of shares | 75 | 79 | 113 | 115 | 126 | 18 |
- † Share count changed about 1/7 in the period ending 2025-12-31, likely a stock split with no split ratio in the XBRL data; figures before that column are not adjusted.
Cash flows
CSVFiscal years (KPTI's year ends in late December)
| In millions of dollars | Dec 31, 2020 | Dec 31, 2021 | Dec 31, 2022 | Dec 31, 2023 | Dec 31, 2024 | †Dec 31, 2025 |
|---|---|---|---|---|---|---|
| Net income (loss) | (196) | (124) | (165) | (143) | (76) | (196) |
| Stock-based compensation | 24 | 30 | 35 | 22 | 18 | 14 |
| Net cash from operating activities | (160) | (107) | (150) | (93) | (127) | (75) |
| Purchases of property and equipment | 0 | 0 | 0 | 0 | 0 | 0 |
| Net cash from investing activities | (54) | 142 | (104) | 8 | 95 | 43 |
| Net cash from financing activities | 172 | 74 | 194 | 1 | 42 | 30 |
| Net change in cash | (42) | 108 | (61) | (84) | 10 | (2) |
- † Share count changed about 1/7 in the period ending 2025-12-31, likely a stock split with no split ratio in the XBRL data; figures before that column are not adjusted.
Compare with peers
SIC 2834 and related industry codes, similar size. Each row is the latest quarter reported.
How peers are chosen
- SIC 2834 and related industry codes with public float (or, where float is missing, quarterly revenue) between 0.2x and 5x the company's.
- Each row is the latest quarter the company has reported, named in the Quarter column; when that filing is a 10-K, it is the fourth quarter, never the full year.
- Runway shows only for companies burning cash with under $10B of public float.
- * marks a quarter worked out from the filing totals: for a 10-K, the year less the first three quarters; for a 10-Q, the year-to-date total less the earlier one.
- A cell reading “not reported” means the filings give no figure for that quarter alone.
| Company | Cash ($M) | Revenue, quarter ($M) | Operating cash flow, quarter ($M) | Shares outstanding | Runway | Quarter |
|---|---|---|---|---|---|---|
| Karyopharm Therapeutics | 55 | 33 | (25)* | 22.7M | 2.6 quarters | 10-QJun 30, 2026 |
| Abvc Biopharma | 0 | not reported | (0.2)* | 26.7M | 0.4 quarters | 10-QJun 30, 2026 |
| BriaCell Therapeutics | 9.9 | not reported | (6)* | 8.7M | 3.4 quarters | 10-KJul 31, 2026 |
| Annovis Bio | 19 | 0* | (22)* | 42.6M | 0.9 quarters | 10-QJun 30, 2026 |
| Atara Biotherapeutics | 3.2 | 0.6 | (3.3)* | 10.0M | 3.0 quarters | 10-QJun 30, 2026 |
| Grace Therapeutics | 14 | not reported | (3.2) | 21.0M | 4.3 quarters | 10-QJun 30, 2026 |
| CervoMed | 22 | 0 | (6.9)* | 15.1M | 3.6 quarters | 10-QJun 30, 2026 |
| Kezar Life Sciences | 66 | not reported | (7.4) | 7.4M | 8.9 quarters | 10-QMar 31, 2026 |
| Actuate Therapeutics | 4.4 | not reported | (4.4)* | 24.0M | 1.0 quarters | 10-QJun 30, 2026 |
Not investment advice. Not affiliated with the U.S. SEC.
